The CCRM Advantage

The Fastest Route to a Healthy Baby

With leading-edge, innovative technology and a team of world-class physicians, CCRM Toronto is able to offer patients the best chance at a successful pregnancy. Through optimal ovarian stimulation, the highest quality blastocysts via day-five transfer, comprehensive chromosomal screening and by ensuring that your uterus is receptive, we are internationally renowned for achieving fastest route to a healthy baby.

Pioneering Technology

Over the last several decades, CCRM has pioneered a paradigm shift in in vitro fertilization (IVF) technology, which has significantly improved pregnancy and birth outcomes for our patients.

  • We developed sequential culture media, to successfully grow embryos to the blastocyst stage (day 5 or 6)
  • We’ve shown that blastocyst stage embryos have markedly higher implantation rates than day 3 embryos
  • We pioneered comprehensive chromosomal screening (testing all 46 chromosomes of the embryo at the blastocyst stage), and have shown that this further improves the success of IVF, while lowering miscarriage rates
  • We successfully vitrify (rapid freezing method) these blastocysts after biopsy with a greater than 98% survival rate

As we began transferring these frozen and thawed chromosomally-normal blastocysts, we found pregnancy rates were higher than we had ever achieved before with IVF, and at the same time miscarriage rates were very low — resulting in significantly higher live birth rates, even for women in their early forties.

Now, the majority of our cycles at CCRM are frozen embryo transfers following culture to the blastocyst stage and comprehensive chromosomal screening. The results are clear: CCRM’s success rates on the SART and CDC websites indicate that our frozen embryo transfer success rates in every age category are among the highest in the world.

CCRM Milestones in Fertility Science

  • 1996 — Pioneered blastocyst culture worldwide with significant improvements to IVF success rates
  • 2007 — First successful blastocyst biopsy in combination with CCS (comprehensive chromosomal screening) worldwide, with significant improvements to IVF success rates
  • 2008 — First baby born from this procedure
  • First clinic worldwide to offer women aged 38-42 significantly improved rates of having a baby through IVF with CCS

Frozen Advantage

Many studies have shown that in vitro fertilization pregnancies following a frozen embryo transfer are more similar to natural conception pregnancies than fresh embryo transfer cycles — resulting in increased implantation rates, increased ongoing pregnancy rates, increased live birth rates, decreased miscarriage rates, a lowered risk of pre-term labor, and healthier babies overall.

Researchers have also found that lengthening the time between administering the drugs and pregnancy lowers a woman’s risk of ovarian hyperstimulation syndrome, a potentially fatal complication that can be triggered by taking certain fertility medications that stimulate egg production.

Single Embryo Transfer (SET)

CCRM’s ultimate goal is to help our patients achieve successful singleton pregnancies. Although twins or “multiples” might seem ideal for those undergoing in vitro fertilization, this scenario poses significant risks for both the mother and children, such as pre-eclampsia, postpartum hemorrhage, maternal mortality, miscarriage, gestational diabetes, as well as pre-term labor. For these reasons, the American Society for Reproductive Medicine recommends single embryo transfer in women younger than 35.